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ISBN : 0470683856
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The latest edition of this highly successful textbook introduces the key techniques and concepts involved in cloning genes and in studying their expression and variation.
The new edition features:
Increased coverage of whole-genome sequencing technologies and enhanced treatment of bioinformatics.
Clear, two-colour diagrams throughout.
A dedicated website including all figures.
Noted for its outstanding balance between clarity of coverage and level of detail, this book provides an excellent introduction to the fast moving world of molecular genetics.
Download latest books on mediafire and other links compilation Free From Genes to Genomes: Concepts and Applications of DNA Technology [Paperback]
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- Paperback: 400 pages
- Publisher: Wiley; 3 edition (December 12, 2011)
- Language: English
- ISBN-10: 0470683856
- ISBN-13: 978-0470683859
- Product Dimensions: 0.6 x 6.5 x 9.2 inches
- Shipping Weight: 1.6 pounds (View shipping rates and policies)
Free From Genes to Genomes: Concepts and Applications of DNA Technology
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The book by Dale, Von Schantz and Platt, From Genes to Genomes, is almost perfect. It is a 350 or so page exceptionally well written book describing all the introductory materials one would need to become current with genomes and genomics efforts. As with many of the other books I had around I first looked at this and at a glance set it aside. Then came the moment when I wanted to re-understand something and I opened this book up and I was hooked. It in a clean and clear manner takes the reader from basic DNA principles and through all of the key techniques used in genomic studies today. It avoids getting to complex into any one area and it reads in a straightforward and consistent manner. It is a superb asset for “catching up” and I suspect for first learning the materials.
Chapter 1 is the basic introduction to genes and genomes. It is DNA 101 but it contains little tidbits of essential materials that are all well integrated. One thus starts with a clear understanding where the authors are taking the reader.
Chapter 2 is the material on basic gene cloning. It uses the plasmid approach with bacteriophage and does so without burdening the reader with too much overhead and history. This Chapter discusses technique and technology and the reader is given a logical approach to the basics of cloning. Restriction enzymes are introduced and the material is adequate to have enough depth to see how they can be applied. There are, of course, a lot of implementation questions that are left hanging but that is typical of this study. There is a section on ligation and I would like to have seen this carried over a bit when discussing gene knock-outs. We can understand how the genes ligate but the question is how well does this carry-over the later processes.
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